A Case Report of Multiple Cylindroma with Immunohistochemical Features

نویسندگان

  • Naoki Watanabe
  • Kana Kawase
  • Chisato Tawada
  • Kazufumi Yoneda
  • Kuniaki Hirai
  • Ayumi Niwa
  • Takuji Tanaka
چکیده

Cylindroma is a benign skin appendageal tumor arising from pluripotent stem cells in the follicle. Multiple cylindroma typically occurs as a component of Brooke-Spiegler syndrome or as the only skin lesion of familial cylindromatosis. We herein report an unusual case of multiple cylindroma involving the trunk without any other features of Brooke-Spiegler syndrome and no family history supporting the possibility of familial cylindromatosis. Immunohistochemical features of CYLD and NF-κB, which are involved in the pathogenesis of cylindroma, in the tumors are also presented.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Intrathoracic Malignant Peripheral Nerve Sheath Tumor: Histopathological and Immunohistochemical Features

Malignant peripheral nerve sheath tumor (MPNST) is a rare nerve sheath tumor derived from Schwann cells or pleuripotent cells of neural crest. Neurogenic tumors make about 10-20% of all mediastinal tumors. Incidence of MPNST is 0.001% in general population and 0.16% in patients with neurofibromatosis I (NF I). We report a case of 60 year female presenting with progressive cough and breathlessne...

متن کامل

Brooke-Spiegler Syndrome: a case report

Brooke-Spiegler syndrome is a rare autosomal recessive disease characterized by adnexal neoplasms, particularly trichoepithelioma, cylindroma, and occasionally spiradenoma, which usually develop in second to third decades of life. We report this syndrome in a 16-year-old woman with tumors on face and scalp.

متن کامل

Malignant spiradenoma/cylindroma of the vulva.

Malignant spiradenoma/cylindroma of the vulva is an extremely rare adnexal tumor. We report the clinicopathological features of a 58-year-old woman who presented with malignant spiradenoma/cylindroma originating in the vulva and metastasized to the inguinal lymph nodes. Surgical excision with adequate margins and lymph node dissection was performed. Sections from the case were stained with Peri...

متن کامل

A Case Report of Gardner's Syndrome and a Review of Literature

  Gardner's syndrome is an autosomal dominant inherited disorder. Familial polyposis of the colon, osteomas, hypertrophy of the retinal-pigmented layer and a multitude of soft tissue tumors are characteristic features. The syndrome may be presented with colonic or extracolonic symptoms. A 75-year-old male patient presented to Al-zahra Clinic with diffuse abdominal pain. An abdominal surgery wa...

متن کامل

معرفی یک مورد سیلندروم پستان و مروری کوتاه بر مقالات پزشکی

Adenoid cystic carcimona of the breast is considered a rare entity with a comparatively favourable prognosis. We report the case of a 44 year old woman and review another 152 cases published to date in the pertinent literature, including two cases from Iran. The diagnosis is made by histological examination which shows the presence of pseudo- cysts encased in cellular masses hespedup, composing...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2016